Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis published in AJHG

There are many types of gene regulation occurring in the human genome that tune not just the level of expression of a gene, but also RNA editing and alternative polyadenylation. These forms of gene regulation are poorly studied during human development. Here, we show that RNA editing and polyadenylation are highly cell type specific, and that genetic variation impacts these post-transcriptional modifications. Our work was published in the American Journal of Human Genetics.