We released a preprint describing organoid modeling of brain growth. Through a collaboration with the Infant Brain Imaging Study, we generated induced pluripotent stem cells (iPSCs) from 18 participants who had undergone longitudinal brain imaging during infancy. We differentiated these iPSCs into cortical organoids and studied how cellular and molecular processes occurring in these brain models in a dish recapitulate the brain growth of the individual from which they were derived. We found that gene expression levels within progenitor cells at the crux of fate decisions - deciding to become a neuron or another progenitor - were critical for determining inter individual differences in brain growth. These findings support the fidelity of cortical organoids as a model system. You can read more about our work here.